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KMID : 0903520090520040401
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2009 Volume.52 No. 4 p.401 ~ p.404
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Accumulation of Intracellular ATP is a Factor Suppressing Morphological Differentiation in Adenosine Kinase Mutant of Streptomyces lividans
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ARISHMA RAJKARNIKAR
Suh Joo-Won
Kwon Hyung-Jin
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Abstract
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The present study demonstrated that the intracellular level of ATP was enhanced up to two-fold and the expression of ramR, a regulatory factor of aerial hyphae development, was repressed in an adenosine kinase mutant of Streptomyces lividans, substantiating that ATP-accumulation is a factor suppressing aerial hyphae development in the mutant.
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KEYWORD
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adenosine kinase mutant, ATP, aerial hyphae development, morphological differentiation, Streptomyces lividans
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